4th December 2019

PTSD and Depression are two Conditions Finally Being Trialled for Treatment with Psilocybin.

A magic mushroom nasal spray has been designed to make microdosing easier for people trying to treat their PTSD or depression.

Silo Wellness, an Oregon based company with product roots in cannabis, has developed a magic mushroom nasal spray in Jamaica (where psilocybin is legal) for controlled, metered-dosing known as ‘microdosing’.

Click here to visit Silo Wellness

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Magic mushroom nasal spray

 

The psilocybin nasal spray passes the gut, going directly to the bloodstream through the nasal membrane and eventually the liver for metabolising. This saves the patient from feeling nauseous, as commonly experienced when taking psilocybin.

Board Advisor and Silo Wellness investor Becky Rotterman, a Missouri pharmacist, stated: “Many psilocybin patients, particularly women, complain of upset stomach or vomiting when taking high-doses of mushrooms.

“We want to bring this wonderful natural medicine first to Oregon and then the flyover states – to those who would be afraid to eat a handful of fungi and who feel more comfortable seeing their medicine in a familiar delivery modality, such as a metered-dose nasal spray.”

The Potential of Psilocybin to Alleviate Psychological and Spiritual Distress in Cancer Patients is Revealed

In addition to the physical pain associated with cancer, many patients also experience psychologically harmful symptoms of anxiety, depression, anger, and denial.  Social isolation, in addition to hopelessness, helplessness and loss of independence, has also been associated with significant psychological suffering in patients coping with advanced-stage cancer.

A recently published book chapter “Use of the Classic Hallucinogen Psilocybin for Treatment of Existential Distress Associated with Cancer,” reviews the potential of a novel psychoactive drug, psilocybin, in alleviating the psychological and spiritual distress that often accompanies a life-threatening cancer diagnosis.

The hallucinogen treatment model with psilocybin has been shown to induce a mystical or spiritual experience and is a unique therapeutic approach to reduce the anxiety of terminal cancer patients.

“Mystical or peak consciousness states in cancer patients have been associated with a number of benefits including improved psychological, spiritual, and existential well-being,” said Dr. Bossis.

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The correct dose

 

  When a patient takes psilocybin the dosage is vital

Many people end up ‘stacking’, whereby the first dose takes some time to take effect so the patient consumes more, only to find they have taken too much later on.

What Schedule Should I Follow?

 

Fadiman recommends taking a microdose once every three days.

Take a microdose on Day 1. Then do not take a microdose on Day 2 or Day 3.

Then, take another microdose on Day 4.

Microdosing alternatives with faster uptake speed are important  in order to prevent accidental high-dosage experiences.

Silo Wellness founder, Mike Arnold, said he created the medicine dispenser after his first experience with psilocybin after he was advised by a doctor to try it.

He said: “I couldn’t help to think how fortunate I was to have an actual physician take me on my first trip rather than ‘some guy’ I know, but I realised that most first-time users don’t have that luxury.

“I reached out to my long-time colleague from the marijuana space, brilliant inventor Michael Hartman, and we agreed that we need to be able to give patients predictable dosing so they can self-titrate into the desired levels of sub-psychedelic or psychedelic treatment.”

“We solved the age-old problem with plant- and fungus-based medicine: How do you know how much is a dose?” Hartman explained. “How do you avoid taking too much, like the cannabis edibles dilemma? We also managed to solve one of the common complaints of some mushroom users: taste and upset stomach.”

Healing trauma with magic mushrooms

Psilocybin has similar action on mind  or awareness healing capabilities as THC or RSO (Rick Simpson oil). Anything that opens the mind has the capacity to increase the neural networks in the brain offering different pathways to unravel last trauma or emotional habits and patterns.

Psilocybin is being trialed for the treatment of a number of physical and mental conditions, two of which are PTSD and depression.

The psychoactive component is thought to stimulate receptors in the brain and potentially ‘rewire the brain’ by increasing neuro connectivity – helping to heal trauma from physical or psychological events.

COO, Scott Slay, said: “We are so grateful for the opportunity to have an actual and real first-to-market consumer product in magic mushrooms.

“I found mushrooms after returning from Iraq working in IED demolition and combat. The war changed me and the VA was ill equipped to help me transition and deal with my PTSD.

“I was heavily medicated. Mushrooms and DMT saved me. My life was renewed. I now have peace and purpose, and I can’t wait to share this opportunity with the world.”

Since psilocybin and other psychoactive compounds are found in nearly 200 known-species of mushrooms, humans have evolved around these beneficial chemical compounds.

Users of psychedelics have known for many years that small “micro doses” of mushrooms can give the user spiritual, medical, and therapeutic benefits without sending the user into a psychedelic ’trip’ as with high doses of mushroom biomass.

Psilocybin for depression has recently been given its second ‘Breakthrough Therapy’ designation by the FDA.

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Flow States

 

A great resource for microdosing LSD is here

All of us, at some point in our lives, have experienced a flow state. The surfer effortlessly riding a big wave, the therapist perfectly in-sync with her client, the salesman elegantly working the room…

Simply put, flow is one of the great experiences of being human.

We have no specific, non-anecdotal evidence to suggest that microdoses of psychedelics can induce flow states – but studies have shown moderate doses of psychedelics cause brain waves to shift toward alpha oscillations, which is also seen in the transition to a flow state [6].

Psychedelics such as LSD imitate the neurotransmitter serotonin when they enter the brain – and we know that serotonin is found in higher levels in flow states. Similarly, LSD increases the levels of dopamine in the brain, [7] another neurotransmitter found in higher levels in flow states.

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“Researchers at the University of Toronto and York University collaborated on the study, which they say is the first of its kind.”

A great study and article is here
The Beckly foundation
Research is ongoing, enroll yourself in a psychedelic study
with the Cancer Anxiety Society  in New York and
Anxiety and Depression related to Cancer Research in Europe 

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